We have fractionated crude porcine heparin to obtain highly active as well as relatively inactive species of molecular weight ≈ 7000 with specific anticoagulant activities of 360 and 12 units/mg, ...
Heparin-induced thrombocytopenia is a prothrombotic drug reaction caused by anti–platelet factor 4 (PF4)–heparin antibodies of the IgG class that activate platelets through platelet Fcγ receptors. 1 ...