A biotech company pioneering transposases for cell line engineering claims to have widened the applications of these tools. Oren Beske, PhD, gave a talk at BioProcess International, about how ATUM is ...

Host Cell Line Selection: The first critical step is selecting the appropriate host cell line. This decision is based on factors such as growth characteristics, genetic stability, and productivity, ...

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide ...

Cell-line development enhances biopharmaceutical production capacity and quality, but complex biologics like bsAbs and ADCs ...

Plant cell-based bioproduction systems are known for producing proteins with proper folding and post-translational modifications that have been used in a handful of approved therapeutics. Widespread ...

Multibillion-dollar gene therapy market facing critical manufacturing bottleneck that limits reach of lifesaving therapies to patients VectorSelect™ platform has the potential to revolutionize the ...

A new proof-of-concept method reliably engineered a hotspot mutation of SF3B1, a gene-splicing gene, into diverse cancer cell lines, outperforming other contemporary editing approaches. Oncogenesis ...

Programmable CRISPR tools are turning stem cell biology into something closer to software engineering, shrinking ...

Cell culture is a fundamental technique in biotechnology and life sciences that involves growing and maintaining living cells outside their natural environment, typically in a controlled laboratory ...